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Home†>†Disease Management
Evidence-Based Medical Monitoring
Evidence-Based Medical Monitoring
Evidence-Based Medical Monitoring
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Monitoring is a major component of management of chronic diseases such as diabetes, cardiovascular disease, arthritis and depression. Yet poor monitoring means healthcare costs are rising.

This book discusses how monitoring principles adopted in other spheres such as clinical pharmacology and evidence-based medicine can be applied to chronic disease in the global setting. With contributions from leading experts in evidence-based medicine, it is a ground-breaking text for all involved in delivery of better and more effective management of chronic illnesses.

Table of Contents


Part 1 The Theory of Monitoring


  1. An introduction to monitoring therapeutic interventions in clinical practice: Paul P. Glasziou (University of Oxford), Jeffrey K. Aronson (University of Oxford)
  2. A framework for developing and evaluating a monitoring strategy: David Mant (University of Oxford)


  3. Developing monitoring tools: integrating the pathophysiology of disease and the mechanisms of action of therapeutic interventions: Jeffrey K. Aronson (University of Oxford), Susan Michie (University College London)
  4. Biomarkers and surrogate endpoints in monitoring therapeutic interventions: Jeffrey K. Aronson (University of Oxford)
  5. Choosing the best monitoring tests: Les Irwig (University of Sydney), Paul P. Glasziou (University of Oxford)


  6. Monitoring the initial response to treatment: Katy Bell (University of Sydney), Jonathan Craig (University of Sydney), Les Irwig (University of Sydney)
  7. Control charts and control limits in long-term monitoring: Petra Macaskill (University of Sydney)
  8. Developing a monitoring schedule: frequency of measurement: Andrew J. Farmer (University of Oxford)
  9. How should we adjust treatment?: Paul P. Glasziou (University of Oxford)


  10. Monitoring as a learning and motivational tool: Susan Michie (University College London), Kirsten McCaffery (University of Sydney), Carl Heneghan (University of Oxford)
  11. Monitoring from the patientís perspective: the social and psychological implications: Kirsten McCaffery (University of Sydney), Susan Michie (University College London)


  12. Evaluating the effectiveness and costs of monitoring: Patrick M.M. Bossuyt (University of Amsterdam)
  13. Good practice in delivering laboratory monitoring: W. Stuart A. Smellie (Bishop Auckland Hospital, County Durham)
  14. Point-of-care testing in monitoring: Christopher P. Price (University of Oxford)
  15. Monitoring for the adverse effects of drugs: Jamie J. Coleman (Queen Elizabeth Hospital, Birmingham), Robin E. Ferner (City Hospital, Birmingham), Jeffrey K. Aronson (University of Oxford)

    Part 2 The Practice of Monitoring

  16. Monitoring diabetes mellitus across the lifetime of illness: Andrew J. Farmer (University of Oxford)
  17. Oral anticoagulation therapy (OAT): Carl Heneghan (University of Oxford), Rafael Perera (University of Oxford)
  18. Monitoring cholesterol-modifying interventions: Paul P. Glasziou (University of Oxford), Les Irwig (University of Sydney), Stephane Heritier (University of Sydney)
  19. Monitoring levothyroxine replacement in primary hypothyroidism: Andrea Rita Horvath (University of Szeged)
  20. Monitoring in renal transplantation: Nicholas B. Cross (University of Sydney), Jonathan Craig (University of Sydney)
  21. Monitoring in pre-eclampsia: Pisake Lumbiganon (Khon Kaen University), Malinee Laopaiboon (Khon Kaen University)
  22. Monitoring in intensive care: Jan M. Binnekade (University of Amsterdam), Patrick M.M. Bossuyt (University of Amsterdam)
  23. Monitoring intraocular pressure in glaucoma: Les Irwig (University of Sydney), Paul R. Healey (University of Sydney), Jefferson DíAssunşăo (University of Sydney), Petra Macaskill (University of Sydney)
  24. Monitoring in osteoarthritis: George Peat (Keele University), Mark Porcheret (Keele University), John Bedson (Keele University), Alison M. Ward (University of Oxford)


Author Information

Professor Paul Glasziou, University of Oxford, Department of Primary Health Care and Director of the Centre for Evidence-based Medicine, Oxford. Paul is a leading figure in evidence-based medicine. He teaches courses and organises workshops both at the Centre in Oxford and the other centres around the world (eg McMaster, Bond University- Australia).

Les Irwig, Professor in the School of Public Health, University of Sydney He teaches courses on diagnostic test assessment, meta-analysis and guideline development, and advanced epidemiological methods. He is especially interested in the application of epidemiological methods to provide the evidence on which to base public health and clinical decisions.

Dr Jeffery Aronson, Clinical Reader in Pharmacology, University of Oxford, UK.

Publication Date: February 2008
Number of Pages: 376
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